Yes, ICAO regulates air cargo operations by setting international standards for safety, security, and transport. These regulations ensure that air cargo is handled safely, following strict procedures for packaging, labeling, and transporting goods. ICAO’s guidelines also address issues such as hazardous materials handling, air cargo security measures, and customs regulations. By implementing these standards, ICAO ensures that air cargo operations remain efficient and safe for both passengers and goods worldwide, maintaining high levels of security across international borders.